(ECS) Discovery The ECS is a biological system composed of endocannabinoids. In 1992 Dr. Raphael Mechoulam, a professor of medical chemistry and natural products was working in the lab at Hebrew University when he stumbled on a startling revelation.
Together with his team, they uncovered a naturally occurring neurotransmitter called anandamide. They kept digging and what they found was remarkable: Anandamide is an “endo” cannabinoid produced in the body, and it is similar in structure and activity to THC derived from cannabis.
From this discovery came a better understanding of these compounds and how they link together and form the ECS. The main role of the ECS is homeostasis or balance in your body and health.
The ECS and Homeostasis
Our bodies are full of cannabinoid receptor sites. The best known are cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2). They keep your brain and body hormones in balance and they do it by either starting or stopping hormonal activity. CB1 receptors can be found in great numbers in your brain, central nervous system, and some organs. CB2 receptors are found in three places: Your gastrointestinal tract (where the majority of your immune health resides), your immune cells themselves, and your peripheral nervous system.
Let’s say you’re suffering from some anxiety. It could be over a job interview, big presentation or a first date. What’s happening in your body is that your anxiety is causing an influx of too much adrenalin. Too many adrenal gland hormones in your system pitch you into a full-blown panic attack. But your ECS can help smooth that out and bring you back in balance by attaching themselves to the correct receptors. Those receptors, in turn, tell your body to stop producing excess adrenaline. The result? You calm down.
The illustration shows CB Receptors and where cannabis can be effective. For some issues, you will need THC with specific CBD/terpenes to impact change. iZeeCBD solutions are designed without THC for a completely relaxing, organic application for health and wellness. THC is needed to cross the blood-brain barrier which triggers the Entourage Effect for CB1 receptors. Therefore, whole plant extract matters, so that all elements within the plant are introduced into your system.
What about using non-THC products, you ask? iZeeCBD uses the whole plant, but since there is less than .3% THC, you will not get the psychotropic effect, or get high, but you will get all the benefits through your CB2 receptors PLUS the supplemental impact of our nutraceutical ingredients.